Knowledge Library
Quality Control for DNA-Encoded One-Bead-One-Compound (OBOC) Libraries
Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology
Drug Discovery: Screening Approaches for Rapid Assessment of Target Tractability
DELpro: A New Method of Hit Discovery
DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug discovery process, allowing access to more chemical space with lower cost. In contrast to high throughput screening, DEL requires a very small amount of target protein and minimum assay development. More importantly, …Read More >
CRISPR Library Screen to Identify Driver Mutations of Tumor Growth and Metastasis
Self Service DNA Encoded Library Screening
DNA-Encoded Libraries in Drug Discovery – Advances in Screening and Chemistry
CRISPR library screens identify frequent cancer mutations regulating PD-1 blockade response
AACR Annual meeting 2021 Wenrong Zhou1,* , Min Long2,3* , Tianyu Song3,* , Qiangqiang Fan1 , Zhengang Peng1 , Yong Cang3 , Qunsheng Ji1 1 Oncology and Immunology Unit, Research Service Division, WuXi AppTec (Shanghai) Co., Ltd., China; 2 Life Sciences Institute, Zhejiang University, Hangzhou, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, …Read More >
Unlocking the potential of DEL | Inspire Hit Discovery
March 4, 2020 – By going commercial, DNA Encoded Library (DEL) technology facilitates rapid discovery and provides access to more chemical entities at lower cost. Over the years, DEL has become a disruptive drug discovery technology in comparison to traditional high-throughput screening (HTS) where it allows expedition of early stage drug discovery. However, DEL platforms don’t succeed …Read More >
Resource Topics
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