Knowledge Library

Quality Control for DNA-Encoded One-Bead-One-Compound (OBOC) Libraries

Resource Type: Video
Resource Topic: DNA-Encoded Library (DEL)

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Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology

Resource Type: Video
Resource Topic: DNA-Encoded Library (DEL)

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Drug Discovery: Screening Approaches for Rapid Assessment of Target Tractability

Resource Type: Webinar
Resource Topic: DNA-Encoded Library (DEL)

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DELpro: A New Method of Hit Discovery

DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug discovery process, allowing access to more chemical space with lower cost. In contrast to high throughput screening, DEL requires a very small amount of target protein and minimum assay development. More importantly, …Read More >

Resource Type: Brochure
Resource Topic: DNA-Encoded Library (DEL)

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Self Service DNA Encoded Library Screening

Resource Type: Webinar
Resource Topic: DNA-Encoded Library (DEL)

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DNA-Encoded Libraries in Drug Discovery – Advances in Screening and Chemistry

Resource Type: Webinar
Resource Topic: DNA-Encoded Library (DEL)

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CRISPR library screens identify frequent cancer mutations regulating PD-1 blockade response

AACR Annual meeting 2021 Wenrong Zhou1,* , Min Long2,3* , Tianyu Song3,* , Qiangqiang Fan1 , Zhengang Peng1 , Yong Cang3 , Qunsheng Ji1  1 Oncology and Immunology Unit, Research Service Division, WuXi AppTec (Shanghai) Co., Ltd., China; 2 Life Sciences Institute, Zhejiang University, Hangzhou, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, …Read More >

Resource Type: Poster
Resource Topic: CRISPR/Cas9 Oncology & Immuno-oncology

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Unlocking the potential of DEL | Inspire Hit Discovery

March 4, 2020 – By going commercial, DNA Encoded Library (DEL) technology facilitates rapid discovery and provides access to more chemical entities at lower cost. Over the years, DEL has become a disruptive drug discovery technology in comparison to traditional high-throughput screening (HTS) where it allows expedition of early stage drug discovery. However, DEL platforms don’t succeed …Read More >

Resource Type: Article
Resource Topic: DNA-Encoded Library (DEL)

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