Knowledge Library

Quantitative Histopathology of Fibrosis in an Animal Model of NASH

The hepatic fibrosis has been the most challenging aspect in the animal models for nonalcoholic steatohepatitis (NASH). Although it could induced by nutritional (high-fat died with high cholesterol, methionine and choline deficient diet, etc), chemical (carbon tetrachloride, thioacetamide, α-naphthylisothiocyanate etc.), and surgical (bile duct ligation) means, the clinical relevance of the resulting fibrosis remains an …Read More >

Resource Type: Article
Resource Topic: Biomarkers Candidate Selection Clinical Bioanalysis Liver Diseases Metabolic Diseases NASH

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Translational Oncology

Biomarker discovery Mouse clinical trial 61 PDX-derived primary cancer cell lines Drug-resistant xenograft models Combination therapy platform including radiation World leading genome sequencing and bioinformatics capability

Resource Type: Brochure
Resource Topic: Biomarkers Candidate Selection Cell-based Assays Cells and Protein Science Chemical Biology and Proteomics Clinical Bioanalysis Lead Optimization Oncology Phenotypic Assays Tumor Models

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Patient-Derived Xenograft (PDX) Tumor Models

One of the largest collection of Patient-Derived Xenograft (PDX) Tumor Models in Asia with genomic profiling 1200 PDX models Collection of PDX models prevalent in Asia 800+ PDX models with genetic profiling Searchable online database with mobile APP Integrated online database for PDX, CDX & Syngeneic tumor models with mobile App PDX with oncogene amplification, …Read More >

Resource Type: Brochure
Resource Topic: Biomarkers Clinical Bioanalysis in vivo Pharmacology Lead Optimization Tumor Models

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WuXi Oncology and Immuno-Oncology Services

Integrated Oncology and Immuno-oncology Platform to Enable Translational Science from Drug Discovery to Clinical Biomarker CRISPR/Cas9 Gene Editing In Vitro Assay and HTS Tumor models Tumor Cell Panel and Screening Immunology and Immuno-oncology Platform Clinical Biomarker

Resource Type: Brochure
Resource Topic: Antibodies Biochemical Assays Biomarkers Cell-based Assays Cells and Protein Science Chemical Biology and Proteomics Clinical Bioanalysis CRISPR/Cas9 Gene Manipulation Gene Therapies High-throughput screening (HTS) Hit-to-Lead Immunology in vitro biology in vivo Pharmacology Lead Optimization Oncology Screening Libraries Small Molecules Target Identification and Validation Target-Specific Assays Targeted Protein Degradation Tumor Models

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Virology and Viral Vector Platforms

WuXi virology platforms: Immunology, Anti viral, Viral Vector, Oligo-nucleotide, Clinical and Immunology in vitro screening and profiling in vivo efficacy clinical virology Liver-specific viruses | Respiratory viruses | Herpes viruses | Other viruses

Resource Type: Brochure
Resource Topic: Biochemical Assays Biomarkers Candidate Selection CAR-T Cell Cell-based Assays Cells and Protein Science Clinical Bioanalysis in vivo Pharmacology in vivo Toxicology Infectious Diseases Lead Optimization Oncolytic Viruses Phenotypic Assays Safety and Early Toxicity

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Clinical Virology

Clinical Virology and Advanced Therapy Platforms Research Services: CAP Accredited Molecular Testing Laboratory Genomics and Biomarker Platform HBV Genotyping Assays HBV Serology Assays HBV Phenotyping Assays Immunological Assays Other Assays:  Oncolytic |  CAR-T/TCR-T Particular Solutions Clinical virology: Viral load, sequencing, genotyping, TCID50, phenotyping, virus isolation and characterization, serology Vaccines: Advanced therapies (Viral vector and cell therapies): …Read More >

Resource Type: Brochure
Resource Topic: Biomarkers Candidate Selection Cell Therapies Cells and Protein Science Clinical Bioanalysis Infectious Diseases Oncolytic Viruses Phenotypic Assays Target-Specific Assays

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