Knowledge Library

WuXi AppTec in vitro Safety Pharmacology Profiling

Comprehensive in vitro Off-target Screening Services WuXi Discovery Biology provides in vitro Safety Pharmacology services to identify potential off-target liabilities. Three choices can be selected: WuXi Biology Mini Safety Panel “WuXi Mini 44” A primary safety panel, which is designed to identify compounds with the highest risk because it contains targets associated with the most …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Cell-based Assays, Lead Optimization, Safety and Early Toxicity, Target-Specific Assays

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in vitro Toxicity Services

Identify potential liability issues in early stages of drug discovery Cardiotoxicity hERG and other ion channel test Stem cell derived cardiomyocyte test on MEA General Cytotoxicity Cell Viability Assay Apoptosis Assay CellTox ™ Green Cytotoxicity Assay ApoTox Glo ™ Triplex Assay Mitochondrial ToxicityMitochondrial Membrane Potential Assay Mitochondrial Reactive Oxygen Species (ROS) Assay Oxygen Consumption Assay: …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Cell-based Assays, Hit-to-Lead, in vitro biology, Lead Optimization, Safety and Early Toxicity

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HBV Discovery Services

A Platform Supporting HBV Drug Discovery A broad assay platform for the discovery of agents for the treatment of chronic HBV infection. Services for assay establishment and validation, compound screening and profiling, and support of preclinical studies and clinical trials. Drug screening using HBV producing cell lines HBV infectious assays Reporter assays Core protein expression …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Cell-based Assays, in vitro biology, in vivo Pharmacology, Infectious Diseases, Lead Optimization

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Resource Topics
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