Poster Archives - Page 9 of 9

Evaluating cancer therapies combining radiotherapy with immunotherapy or inhibitors of the DNA damage response

Ionizing radiation has largely been recognized as a local targeted therapy by a variety of mechanisms, including inducing direct DNA...

Evaluation of the efficacy of ADC in vitro and in vivo

Abstract Antibody drug conjugates (ADCs) are promising complexes with therapeutic potential that aimed to the treatment of solid tumor and...

Validation of GVHD in mouse model for preclinical efficacy screen

AACR Annual meeting 2021 Na Xu, Ya Zhang, Rou Xie, Lijun Jia, Yingying Cai, Qing Lin Oncology and Immunology Unit,...

Engineered cell line panel complemented with in vivo models to enable next-generation target therapy discovery...

AACR Annual meeting 2021 Authors: Zhixiang Zhang1, Feifei Fan2, Xiaohe Shi2, Xiangyang Zuo2, Qingyang Gu2, Qunsheng Ji1. 1 WuXi AppTec,...

Establishment of drug induced resistant tumor models enable the development of next generation anticancer therapeutics

AACR Annual meeting 2021 Ting Ni, Zhixiang Zhang, Xuzhen Tang, Hui Qi, Jingying Zhang, Ke Mao, Wenting Shi, Qingyang Gu,...

Establishment of KRAS-G12C inhibitor induced resistant tumor models enable the development of new generation KRAS-G12C...

Activating KRAS mutations, including G12C and G12D, are detected in approximately 25% of human cancers. The most common KRAS mutation...

Establishment and Optimization of scRNA-seq assay to find the mechanism of immune therapy against tumors

Tumors are complex ecosystems composed of different cell types with different phenotypes, status and gene profiles. Commonly used GEP tools...

Identification of Tofacitinib, Filgotinib and Ruxolitinib on experimental Sjögren’s syndrome model in mice

Sjögren’s syndrome, which affects hundreds of millions of people worldwide, is a chronic autoimmune disorder characterized by leukocytic infiltration into...

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