Knowledge Library

Outsourcing Drug Discovery and Development: Considerations For Emerging Biopharma Companies

Resource Type: White Paper
Resource Topic: Candidate Selection, Discovery Chemistry, DRUG DISCOVERY AND INNOVATION, Hit Finding, Hit-to-Lead, Lead Optimization, Target Identification and Validation

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Quantum Mechanics for Organic Chemists: An Experimentalist Approach

Magical Power of Quantum Mechanics EBook Would you like to predict organic reaction outcomes accurately? Design synthetic sequences with higher rate of success? Would you prefer to learn and rationalize organic chemistry in a data-driven manner? Quantum Mechanics (QM) tools for chemistry are evolving at a tremendously fast pace and have proven to be invaluable for …Read More >

Resource Type: Ebook
Resource Topic: Discovery Chemistry, in silico services, Quantum Mechanics, Small Molecules

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Targeted Protein Degradation Platform

Integrated Services BIOLOGY & PHARMACOLOGY BINARY/TERNARY COMPLEX FORMATION Biochemical & Biophysical Assays Biochemical binding assay Cellular Assays TARGET UBIQUITINATION & DEGRADATION In vitro Assays-Target ubiquitination Target degradation assay PK/PD Animal Disease Model Evaluation CHEMISTRY Specific virtual library design Compound synthesis Conjugation and all type of custom syntheses from milligram to kilogram scale Purification and analytical …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Discovery Chemistry, Hit-to-Lead, Lead Optimization, Small Molecules, Targeted Protein Degradation

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Antibody and Protein Preparation Services

Integrated Drug Discovery Platform for Antibody & Protein Preparation We are dedicated to offering an integrated and cost-effective services platform of polyclonal and monoclonal antibodies, including: Antigen design and preparation Anti-drug antibodies (ADA) Host cell protein (HCP) antibodies Surrogate antibodies Diagnostic antibodies Therapeutic antibodies Learn about our services platform for evaluating bispecific antibodies

Resource Type: Brochure
Resource Topic: Antibodies, Cells and Protein Science, Immunology, Target Identification and Validation

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One-stop DEL services from target to hit series – DELpro

WuXi AppTec  provides a one-stop solution for DEL services from target to hit series. Our extended platform enables overall planning and management of protein production, DEL library production, affinity selection, data analysis, hit validation and structural biology for further optimization.

Resource Type: Brochure
Resource Topic: Biophysical Assays, Cells and Protein Science, Discovery Chemistry, DNA-Encoded Library (DEL), Hit Finding, Hit-to-Lead, Small Molecules, Target Identification and Validation

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Open Access to DEL for data sharing – DELopen

DELopen platform is dedicated to the development and application of DEL technology in drug discovery. Free access to DEL, data sharing. DELopen encourages an open, community-based approach to data sharing and exploration of the capabilities of DEL technology. We envision that DELopen will help academia benefits from the efficiency of DEL and unlock the full …Read More >

Resource Type: Brochure
Resource Topic: Discovery Chemistry, DNA-Encoded Library (DEL), Hit Finding, Screening Libraries, Small Molecules, Target Identification and Validation

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DNA-encoded libraries for academic – DELopen Handbook

DNA-encoded libraries for academic | Open Access to DEL Self-service platform for academia to utilize the full potential of DEL technology DELopen provides free access to DNA-encoded libraries (DEL) for academic users and encourages an open, community-based approach to data sharing.

Resource Type: Brochure
Resource Topic: Discovery Chemistry, DNA-Encoded Library (DEL), Hit Finding, Screening Libraries, Small Molecules, Target Identification and Validation

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DEL Screening – DELight Handbook

DEL Screening | WuXi AppTec DELight Kit  Faster and Lighter Drug Discovery DELight kit containing 58 libraries and 10.8 billion compounds, buffers and a step-by-step online experimental manual. Drug developers perform affinity selection according to the manual and return the sample to WuXi AppTec upon completion.

Resource Type: Brochure
Resource Topic: Chemical Biology and Proteomics, DNA-Encoded Library (DEL), Hit Finding, Screening Libraries, Small Molecules, Target Identification and Validation, Targeted Protein Degradation

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Translational Oncology

Biomarker discovery Mouse clinical trial 61 PDX-derived primary cancer cell lines Drug-resistant xenograft models Combination therapy platform including radiation World leading genome sequencing and bioinformatics capability

Resource Type: Brochure
Resource Topic: Biomarkers, Candidate Selection, Cell-based Assays, Cells and Protein Science, Chemical Biology and Proteomics, Lead Optimization, Oncology, Phenotypic Assays, Tumor Models

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Resource Topics
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