G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes and play a pivotal role in signaling pathways, making these transmembrane proteins an important drug target class.  In recent years, GPCR drug discovery has moved from random ligand screening towards structure-based drug design. WuXi Biology has developed an integrated GPCR …Read More >

WuXi AppTec  | Target-to-Hit Solutions Protein Production  | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms |  Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening

DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug discovery process, allowing access to more chemical space with lower cost. In contrast to high throughput screening, DEL requires a very small amount of target protein and minimum assay development. More importantly, …Read More >