DELvision: A Protein-DEL Interaction Database
Currently, there is a lack of efficient experimental strategies to collect high-quality proteome level data for protein-ligand interactions (PLIs). At the 2024 ML Drug Discovery Symposium, WuXi AppTec presented a poster showcasing our advanced DELvision database, representing the first use of DNA-encoded library (DEL) technology for establishing a protein-DEL interaction database.
The authors demonstrate how DEL can be applied for profiling vast small molecule chemical spaces for their binding capabilities with thousands of proteins. In this manner, the DELvision database can contribute to bridging the gap between a large chemical space and the druggable genome.
Poster_Machine Learning in Drug Discovery Symposium_DELvision
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